Protein name:
Kelch-like ECH-associated protein 1 ;
Alternative:
Cytosolic inhibitor of Nrf2 (INrf2) ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Homodimer. Forms a ternary complex with NFE2L2 and PGAM5. Interacts with the N-terminal regulatory domain of NFE2L2/NRF2. Interacts with BPTF and PTMA. Interacts with CUL3. Part of a complex that contains KEAP1, CUL3 and RBX1.
Function:
Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Subcellular Location:
Cytoplasm
Nucleus
Shuttles between cytoplasm and nucleus.
Protein Attributes:
50:
MQPEPRPSGA | GAHTQFLPLR | SQRPEGAGDT | VMYASTECKA | EVTPSQHGNR |
100:
TFSYTLEDHT | KQAFGIMNEL | RLSQQLCDVT | LQVKYEDAPA | AQFMAHKVVL |
150:
ASSSPVFKAM | FTNGLREQGM | EVVSIEGIHP | KVMERLIEFA | YTASISMGEK |
200:
CVLHVMNGAV | MYQIDSVVRA | CSDFLVQQLD | PSNAIGIANF | AEQIGCAELH |
250:
QRAREYIYMH | FGEVAKQEEF | FNLSHCQLVT | LISRDDLNVR | CESEVFHACI |
300:
NWVKYDCEQR | RFYVQALLRA | VRCHSLTPHF | LQMQLQKCEI | LQSDSRCKDY |
350:
LVKIFQELTL | HKPTQVMPCR | APKVGRLIYT | AGGYFRQSLS | YLEAYNPSDG |
400:
TWLRLADLQV | PRSGLAGCVV | GGLLYAVGGR | NNSPDGNTDS | SALDCYNPMT |
450:
NQWSPCAPMS | VPRNRIGVGV | IDGHIYAVGG | SHGCIHHNSV | ERYEPERDEW |
500:
HLVAPMLTRR | IGVGVAVLNR | LLYAVGGFDG | TNRLNSAECY | YPERNEWRMI |
550:
TPMNTIRSGA | GVCVLHNCIY | AAGGYDGQDQ | LNSVERYDVE | TETWTFVAPM |
600:
KHRRSALGIT | VHQGRIYVLG | GYDGHTFLDS | VECYDPDTDT | WSEVTRMTSG |
624:
RSGVGVAVTM | EPCRKQIDQQ | NCTC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Pig
Mouse
ELISA Kit for Pig Kelch-like ECH-associated protein 1
ELISA Kit for Pig Kelch-like ECH-associated protein 1
ELISA Kit for Pig Kelch-like ECH-associated protein 1
ELISA Kit for Pig Kelch-like ECH-associated protein 1
CLIA Kit for Pig Kelch-like ECH-associated protein 1
CLIA Kit for Pig Kelch-like ECH-associated protein 1
CLIA Kit for Pig Kelch-like ECH-associated protein 1
CLIA Kit for Pig Kelch-like ECH-associated protein 1
Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
Protein for Pig Kelch-like ECH-associated protein 1
Protein for Pig Kelch-like ECH-associated protein 1
Protein for Pig Kelch-like ECH-associated protein 1
Protein for Pig Kelch-like ECH-associated protein 1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]