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Index > Protein center > KEAP1(Gene name) > Pig
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  • KEAP1 (Gene name),
  • Kelch-like ECH-associated protein 1 (Protein name ),  KEAP1_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    KEAP1(INRF2);
    Protein name:
    Kelch-like ECH-associated protein 1;
    Alternative:
    Cytosolic inhibitor of Nrf2(INrf2);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Homodimer. Forms a ternary complex with NFE2L2 and PGAM5. Interacts with the N-terminal regulatory domain of NFE2L2/NRF2. Interacts with BPTF and PTMA. Interacts with CUL3. Part of a complex that contains KEAP1, CUL3 and RBX1.
    Function:
    Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
    Subcellular Location:
    Cytoplasm Nucleus Shuttles between cytoplasm and nucleus.
    Protein Attributes:
    Sequence length:
    624
    Sequence:
    50:
    MQPEPRPSGA | GAHTQFLPLR | SQRPEGAGDT | VMYASTECKA | EVTPSQHGNR | 
    100:
    TFSYTLEDHT | KQAFGIMNEL | RLSQQLCDVT | LQVKYEDAPA | AQFMAHKVVL | 
    150:
    ASSSPVFKAM | FTNGLREQGM | EVVSIEGIHP | KVMERLIEFA | YTASISMGEK | 
    200:
    CVLHVMNGAV | MYQIDSVVRA | CSDFLVQQLD | PSNAIGIANF | AEQIGCAELH | 
    250:
    QRAREYIYMH | FGEVAKQEEF | FNLSHCQLVT | LISRDDLNVR | CESEVFHACI | 
    300:
    NWVKYDCEQR | RFYVQALLRA | VRCHSLTPHF | LQMQLQKCEI | LQSDSRCKDY | 
    350:
    LVKIFQELTL | HKPTQVMPCR | APKVGRLIYT | AGGYFRQSLS | YLEAYNPSDG | 
    400:
    TWLRLADLQV | PRSGLAGCVV | GGLLYAVGGR | NNSPDGNTDS | SALDCYNPMT | 
    450:
    NQWSPCAPMS | VPRNRIGVGV | IDGHIYAVGG | SHGCIHHNSV | ERYEPERDEW | 
    500:
    HLVAPMLTRR | IGVGVAVLNR | LLYAVGGFDG | TNRLNSAECY | YPERNEWRMI | 
    550:
    TPMNTIRSGA | GVCVLHNCIY | AAGGYDGQDQ | LNSVERYDVE | TETWTFVAPM | 
    600:
    KHRRSALGIT | VHQGRIYVLG | GYDGHTFLDS | VECYDPDTDT | WSEVTRMTSG | 
    624:
    RSGVGVAVTM | EPCRKQIDQQ | NCTC
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    E2835r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    E2835h
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    E2835p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    E2835m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    U2835r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    U2835p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    U2835h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Kelch-like ECH-associated protein 1
    Cat.:
    U2835m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Cat.:
    P2835Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Cat.:
    P2835Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Cat.:
    P2835Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Monoclonal Antibody for Pig Kelch-like ECH-associated protein 1
    Protein for Pig Kelch-like ECH-associated protein 1
    Protein for Pig Kelch-like ECH-associated protein 1
    Protein for Pig Kelch-like ECH-associated protein 1
    Protein for Pig Kelch-like ECH-associated protein 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular characterization of the porcine TYK2 gene on SSC 2q1.3 -> q2.1."
      Leeb T. , Martins-Wess F. , Kuiper H. , Lassnig C. , Distl O. , Mueller M.
      Cytogenet. Genome Res.107:103-107(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
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